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Compound library

GHK-Cu

A copper-binding tripeptide first isolated from human plasma.

MW 401.91 CAS 89030-95-5 ≥99.0% (HPLC)

A copper-binding tripeptide first isolated from human plasma.

What it is

GHK is a tripeptide first isolated from human plasma in 1973. It binds copper(II) with high affinity, and the resulting complex, GHK-Cu, is the form most often used in research.

GHK-Cu has been studied in cell-culture and animal models of wound repair, collagen and glycosaminoglycan synthesis, and skin biology. Gene-expression studies in cultured cells have reported broad effects on transcription, making it a subject of interest in tissue-remodelling research.

The lyophilized powder is blue, as expected for the copper complex.

Specifications

SequenceGly His Lys Cu²⁺
Molecular formulaC14H22CuN6O4
Molecular weight401.91
CAS number89030-95-5
Purity specification≥99.0% (HPLC)
Storage−20 °C, sealed, protected from light

How it is handled in the lab

Supplied lyophilized. Warm the sealed vial to room temperature before opening, reconstitute in a solvent suited to the sequence, and divide into single-use aliquots. See our Storage & Handling guide.