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Compound library

Semax

A heptapeptide built from the ACTH(4-7) fragment.

MW 813.93 CAS 80714-61-0 ≥99.0% (HPLC)

A heptapeptide built from the ACTH(4-7) fragment.

What it is

Semax is a synthetic heptapeptide consisting of the ACTH(4-7) fragment (Met-Glu-His-Phe) followed by Pro-Gly-Pro. It lacks the corticotropic (hormonal) activity of full-length ACTH.

Research, mostly in rodents, has examined Semax in models of cerebral ischemia and for its effects on the expression of brain-derived neurotrophic factor (BDNF) and its receptor TrkB.

Specifications

SequenceMEHFPGP
Molecular formulaC37H51N9O10S
Molecular weight813.93
CAS number80714-61-0
Purity specification≥99.0% (HPLC)
Storage−20 °C, sealed, protected from light

How it is handled in the lab

Supplied lyophilized. Warm the sealed vial to room temperature before opening, reconstitute in a solvent suited to the sequence, and divide into single-use aliquots. See our Storage & Handling guide.