Compound library
Ipamorelin
A selective pentapeptide agonist of the ghrelin receptor.
MW 711.85 CAS 170851-70-4 ≥99.0% (HPLC)
A selective pentapeptide agonist of the ghrelin receptor.
What it is
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue developed in the late 1990s. It contains non-standard residues, including aminoisobutyric acid (Aib) and D-2-naphthylalanine, and a C-terminal amide.
In early pharmacology studies it stimulated growth hormone release in animal models through the ghrelin receptor (GHS-R1a), with notable selectivity: it showed little effect on ACTH or cortisol release compared with earlier secretagogues. It remains a common tool for studying GHS-R1a signalling.
Specifications
| Sequence | Aib His D-2Nal D-Phe Lys NH₂ |
|---|---|
| Molecular formula | C38H49N9O5 |
| Molecular weight | 711.85 |
| CAS number | 170851-70-4 |
| Purity specification | ≥99.0% (HPLC) |
| Storage | −20 °C, sealed, protected from light |
How it is handled in the lab
Supplied lyophilized. Warm the sealed vial to room temperature before opening, reconstitute in a solvent suited to the sequence, and divide into single-use aliquots. See our Storage & Handling guide.